NFL DFS: Optimal DraftKings, FanDuel daily Fantasy football picks, stacks, strategy for Week 5, 2022

After disappointing daily fantasy football players for the first three weeks, Chargers running back Austin Ekeler had a breakout game in Week 4. Ekeler hadn’t found the end zone previously, but he notched three touchdowns along with 109 scrimmage yards against the Texans. Now, the stud running back has a matchup against the player who’s been the most productive NFL DFS back all season, Nick Chubb of the Browns. You could realistically roster both running backs in Chargers vs. Browns for your Week 5 NFL DFS lineups, although that would leave you cash-strapped at other positions.

Thus, you would then need to search for value elsewhere in the NFL DFS player pool for players like Titans wide receiver Robert Woods. He isn’t among the 30 most expensive wideouts on either FanDuel or DraftKings, but faces a Lions defense that’s allowed the second-most Fantasy points to opposing wide receivers. Before you make your NFL DFS picks for Week 5, be sure to see the NFL DFS advice, strategy and player projections from SportsLine daily Fantasy expert Mike McClure.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1% in more than a dozen other tournaments.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values ‚Äč‚Äčthat he shares only with members at SportsLine.

This year, he’s already won the DraftKings Millionaire Maker, crushing the Rams vs. 49ers Monday Night Football game. Now, McClure has turned his attention to Sunday’s Week 5 slate and locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Week 5

One of McClure’s top NFL DFS picks for Week 5 is 49ers running back Jeff Wilson Jr. at $5,500 on DraftKings and $6,500 on FanDuel. Wilson is coming off 74 yards and a touchdown in a Monday night win and is running in a way that indicates he might not give back the starting job once Elijah Mitchell (knee) returns. Over his last three games, Wilson has averaged 94.3 yards per game with a 4.9 rushing average.

That yardage is nearly identical to the 95.3 yards that Week 5 opponent Carolina has allowed to opposing starting running backs this season. The Panthers rank 25th in run defense, and three of the four starting running backs they have faced have set their season-highs in rushing yards versus Carolina. San Francisco is one of a handful of NFL teams that has run the ball more times than passing the ball, and Wilson will be the primary benefactor of that offensive game plan on Sunday.

Part of McClure’s optimal NFL DFS strategy includes rostering Buccaneers running back Leonard Fournette at $6,900 on DraftKings and $7,800 on FanDuel. Tampa all but ignored the run in last week’s loss, but Fournette made an impact through the air with 57 yards and a touchdown. He is the focal point of the Bucs’ offense, ranking ninth in the NFL in touches and averaging 83.8 scrimmage yards per game.

Fournette has hit paydirt three times in his last four games versus the Falcons. He’s primed to both rack up yardage and find the endzone on Sunday after Atlanta gave up 195 total yards and one touchdown to Nick Chubb and Kareem Hunt last week. You can see the rest of McClure’s NFL DFS advice here.

How to make NFL DFS lineups for Week 5

McClure is also targeting another undervalued option that could explode for huge numbers. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of McClure’s NFL DFS picks, at SportsLine.

Who is Mike McClure including in his optimal NFL DFS lineups for Sunday’s Week 5 slate? And which under-the-radar player is a must-roster? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who has won millions with his daily Fantasy picks, and find out.